Individual variations in arsenic metabolism in Vietnamese: the association with arsenic exposure and GSTP1 genetic polymorphism
Some new substituted benzaldehyde (2,3,4,6-tetra-O-acetyl-a-D-galactopyranosyl) thiosemicarbazones were synthesised by reaction of 2,3,4,6-tetra-O-acetyl-a-D-galactopyranosyl thiosemicarbazide and different substituted benzaldehydes. The reaction was performed using conventional and microwave-assisted heating methods. The structures of thiosemicarbazones were confirmed by spectroscopic (IR, H-1 NMR, C-13 NMR and MS) method. The antioxidant activity of these thiosemicarbazones was evaluated, in vitro and in vivo, and it's shown that some of these compounds had significant antioxidant activity. Title: Individual variations in arsenic metabolism in Vietnamese: the association with arsenic exposure and GSTP1 genetic polymorphism Authors: Nguyen, Minh Tue Vi, Thi Mai Lan Pham, Thi Kim Trang Pham, Hung Viet Tetsuro Agusa Keywords: Antioxidant activity D-galactose microwave-assisted thiosemicarbazones thiosemicarbazones Issue Date: 2012 Publisher:...